FEISTYII

FEISTYII

Fibrinogen Early In Severe Trauma Study

Emergency Department Trauma

A randomised controlled trial

AIMS

A study to investigate if fibrinogen replacement using FIBRINOGEN CONCENTRATE improves outcomes for patients with major haemorrhage following trauma compared to CRYOPRECIPITATE

Inclusion Criteria

Exclusion Criteria

1. Adult (>18yrs) affected by trauma

2. Judged to have significant haemorrhage.

3. Activation of local MTP and/or transfusion of emergency blood products

4. FIBTEM A5 <10mm

1.Injury judged incompatible with survival

2.Inability to randomise <6 hours of presentation to hospital

3.Known pregnancy

4.Known genetic or drug induced coagulation disorders

5.Known objection to blood products

6.Prior FC or Cryo at recruiting Trauma Centre

7.Severe pre-existing physical or mental disability or co-morbidity that may interfere with outcome assessment.

8.Participation in a competing study.

What you need to do:

Any patient that meets inclusion criteria either:
- Randomise the patient or
- contact the research team on 28608 to assist
To Randomise a patient:
Log onto http://data.feisty.org.au User Name: feisty2darwin Password: darwinfeisty2
- Randomise the patient
- Print randomisation result
- Grab the relevant study arm pack from research draw in resus (dependent on which arm the patient was randomised to)
- Patient to stay on allocated arm for Maximum 24 hours if in ED/ICU

Further Questions

Prinicipal Investigator: Dr Sandra Brownlea This email address is being protected from spambots. You need JavaScript enabled to view it.
- Megan Duck; Research Coordinator (This email address is being protected from spambots. You need JavaScript enabled to view it.) 28608
- Hanna Bjoern; Research nurse (hanna.bjoernThis email address is being protected from spambots. You need JavaScript enabled to view it.) 27969
- This email address is being protected from spambots. You need JavaScript enabled to view it. 0460 034 800